Cure Pancreatic Cancer Naturally



Antioxidants May Limit Pancreatic Cancer Risk

Regimen of vitamins C and E and selenium yielded best results.

By Charles Bankhead, MedPage Today

Medically Reviewed by Robert Jasmer, MD

Don't Miss This

Sign Up for OurCancer Care and PreventionNewsletter

Thanks for signing up!You might also like these other newsletters:

TUESDAY, July 24, 2012 (MedPage Today) —The risk of pancreatic cancer declined significantly as intake of antioxidants increased among participants in a large case-control study.

The magnitude of risk reduction varied by the quantity and types of antioxidants but reached a maximum of 67 percent in people who had the greatest intake of vitamins C and E and selenium.

The data suggested a threshold effect for selenium and a trend toward a threshold effect for vitamin E, as well as a significant inverse association between pancreatic cancer risk and serum levels of vitamin C.

"The results support measuring antioxidants in studies investigating the etiology of pancreatic cancer," Andrew R. Hart, MD, of the University of East Anglia in Norwich, and co-authors wrote in conclusion in an article published online inGut. "If the association is causal, one in 12 cancers might be prevented by avoiding the lowest intakes (of antioxidants)."

Most patients with pancreatic cancer have a poor prognosis, owing in large part to late diagnosis and poor understanding of the disease's etiology. Factors associated with an increased pancreatic cancer include a family history of the disease, smoking, type 2 diabetes, chronic pancreatitis, andHelicobacter pyloriinfection, according to background information in the article.

Pancreatic cancer risk has an inverse association with use of aspirin and statins, however, and dietary factors might also influence the risk. In particular, several plausible biological mechanisms suggest a possible role for antioxidants in the cancer risk. But the few cohort studies that have examined associations have produced mixed results.

Hart and colleagues undertook a study to evaluate links between antioxidant intake and pancreatic cancer risk on the basis of data from 7-day food diaries. They study involved 23,658 participants in the European Prospective Investigation of Cancer (EPIC) Norfolk Study, which spanned the years 1993 to 1997.

Study participants were enrolled from 35 general medical practices in Norfolk County, England. The cohort comprised men and women ages 40 to 74 at the time of enrollment.

Each participant had a baseline physical examination, during which blood samples were drawn. Additionally, study nurses explained how to complete the 7-day food diary. Completed diaries were evaluated and coded by trained nutritionists.

EPIC-Norfolk participants were followed to June 2010, and new diagnoses of pancreatic cancer were identified from regional health authority records and a cancer registry. Participants were excluded from the cancer analysis if uncertainty existed about the diagnosis, if the cancer was present at enrollment, or if the diagnosis occurred during the first year of follow-up.

Investigators determined that 49 EPIC-Norfolk participants developed pancreatic cancer during follow-up. The patients were compared with a control group of 3,970 participants who did not have pancreatic cancer.

Patients and the control group were separated into quartiles of intake for vitamin C, vitamin E, selenium, and zinc. Those who were in the highest three quartiles for each of vitamins C and E and selenium had a 67 percent reduction in the hazard for pancreatic cancer as compared with participants in the lowest quartile.

Among the individual antioxidant nutrients, a significant threshold effect (quartiles 2 through 4 versus quartile 1) was seen for selenium, and a trend was evident for vitamin E. With the exception of zinc, individual quartiles (2 through 4 versus 1) of antioxidant intake were less than 1.

Serum levels of vitamin C had a significant inverse association with pancreatic cancer risk, but not a threshold effect of intake as determined by 7-day food diaries.

"The current evidence from etiological epidemiological work is minimal and inconsistent, although our work using an accurate method of dietary assessment and other studies using biomarkers of antioxidants suggest that vitamins C and E and selenium may be protective," the authors wrote in conclusion.






Video: The fruit that is 10,000 times stronger than Chemotherapy! Soursop / Guanabana Graviola

Antioxidants May Limit Pancreatic Cancer Risk
Antioxidants May Limit Pancreatic Cancer Risk images

2019 year
2019 year - Antioxidants May Limit Pancreatic Cancer Risk pictures

Antioxidants May Limit Pancreatic Cancer Risk recommend
Antioxidants May Limit Pancreatic Cancer Risk forecasting photo

Antioxidants May Limit Pancreatic Cancer Risk foto
Antioxidants May Limit Pancreatic Cancer Risk pictures

Antioxidants May Limit Pancreatic Cancer Risk Antioxidants May Limit Pancreatic Cancer Risk new foto
Antioxidants May Limit Pancreatic Cancer Risk new images

pictures Antioxidants May Limit Pancreatic Cancer Risk
images Antioxidants May Limit Pancreatic Cancer Risk

Watch Antioxidants May Limit Pancreatic Cancer Risk video
Watch Antioxidants May Limit Pancreatic Cancer Risk video

Discussion on this topic: Antioxidants May Limit Pancreatic Cancer Risk, antioxidants-may-limit-pancreatic-cancer-risk/
Forum on this topic: Antioxidants May Limit Pancreatic Cancer Risk, antioxidants-may-limit-pancreatic-cancer-risk/ , antioxidants-may-limit-pancreatic-cancer-risk/

Related News


Exclusive: Body-Shamed Model Charli Howard Is Fighting Back with Clever NewCampaign
How to Get out of a Headlock
How to Feed an Elderly Relative in the Hospital
When a Second Chronic Condition Complicates Multiple Sclerosis
How to Appear to Have Snow Power
How to Make Soursop Juice
Latex Allergy Symptoms (and What to Do If You Have One)
The feud between Charles and the Middletons over Prince George, Louis, and Princess Charlotte
How to (Safely) Look for and Have No-Strings-Attached Sex
George Seamless Shaping Slimmer Plus
Who Should Not Drink Turmeric Milk in Hindi
How to Write a Horror Movie
Dear Whys Guy: How Do I Know if My Ex Wants Me Back
Square-Toe Shoes Are Giving Pointed-Toe Shoes a Run for TheirMoney



Date: 16.12.2018, 12:48 / Views: 51342